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Healthcare 2026Updated

List of Regulated Psychedelic-Assisted Therapy Clinics

Directory of legally operating psychedelic-assisted therapy clinics across the United States, including ketamine infusion centers, Oregon psilocybin service centers, and Colorado natural medicine healing centers with verified licensing and regulatory compliance data.

Available Data Fields

Clinic Name
Treatment Modalities
Licensing Status
Location
Regulatory Jurisdiction
Substances Offered
Contact Information
Website
Accreditation
Conditions Treated

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Clinic NameTreatment ModalitiesLocationLicensing Status
Ketamine Clinics of Los Angeles (KCLA)IV Ketamine Infusion, TMSLos Angeles, CAQuad A Accredited
Nushama Psychedelic WellnessIV Ketamine InfusionNew York, NYState Licensed
Ember HealthIV Ketamine InfusionNew York, NY (5 locations)State Licensed
Emergence Psychedelic TherapyPsilocybin-Assisted TherapyBoulder, COCO Micro Healing Center License
MindbloomAt-Home Sublingual Ketamine37 States + DC (Telehealth)State Licensed (Multi-State)

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Navigating the Regulated Psychedelic Therapy Landscape

The regulated psychedelic therapy market in the United States has expanded rapidly, with over 1,500 clinics operating under various legal frameworks as of 2026. The vast majority offer ketamine — the only psychedelic-adjacent substance broadly legal for off-label psychiatric use — while a smaller but growing number operate under state-level psilocybin programs in Oregon and Colorado.

Legal Frameworks by Substance

Ketamine
Federally legal as a Schedule III controlled substance. Any licensed physician can prescribe it off-label for psychiatric conditions. This has enabled rapid clinic growth from fewer than 100 in 2015 to over 1,500 by 2024. Delivery methods include IV infusion, intramuscular injection, sublingual lozenges, and FDA-approved esketamine nasal spray (Spravato).
Psilocybin
Legal only in Oregon (since 2023) and Colorado (since 2025) under state-regulated programs. Oregon licenses service centers and facilitators through the Oregon Psilocybin Services program, though roughly a third of originally licensed centers have since closed. Colorado has approved 34 state-licensed healing centers across standard and micro-license tiers.
MDMA
Not yet FDA-approved. An FDA advisory panel voted against approval for MDMA-assisted therapy for PTSD in 2024. Clinical trials continue, and Medicare pilot programs were anticipated between 2025–2026.

Clinic Operating Models

ModelExampleTypical Cost per Session
In-clinic IV infusionKCLA, Ember Health$400–$800
Telehealth + at-home lozengesMindbloom, Joyous$165–$215
Psilocybin service centerOregon OPS licensees$1,500–$3,500
Micro healing centerColorado micro-licensees$1,000–$2,500

Key Regulatory Considerations

Licensing requirements vary significantly by jurisdiction and substance. Ketamine clinics must maintain DEA registration and comply with state medical board regulations. Oregon psilocybin centers require OPS licensing with specific facility, facilitator, and safety protocol requirements. Colorado distinguishes between standard and micro healing center licenses, with micro-licenses designed for lower-volume operations integrated into existing wellness practices.

Accreditation adds another layer of differentiation — the Quad A (AAAHC) accreditation, for example, signals compliance with ambulatory surgery center standards, though it is held by only a small fraction of ketamine clinics nationwide.

Frequently Asked Questions

Q.Which psychedelic substances are legal for therapeutic use in the US?

Ketamine is the only broadly legal option, available off-label nationwide via licensed physicians. Psilocybin is legal under regulated programs in Oregon and Colorado. MDMA-assisted therapy has not received FDA approval. All other psychedelics remain federally prohibited outside of clinical trials.

Q.How is clinic licensing verified in this dataset?

Licensing data is sourced from public records including state medical boards, the Oregon Psilocybin Services licensee directory, Colorado Department of Regulatory Agencies filings, and DEA registration databases. Data is collected by AI at the time of your request from publicly available sources.

Q.Does the dataset include telehealth-only ketamine providers?

Yes. The dataset covers both brick-and-mortar clinics and telehealth platforms that prescribe at-home ketamine treatment. Each entry specifies the delivery model so you can filter by in-person, telehealth, or hybrid.

Q.Are clinics outside the United States included?

This dataset focuses on US-based clinics operating under US regulatory frameworks. International psychedelic therapy centers (e.g., Jamaica, Netherlands, Costa Rica) are covered in separate datasets.

Q.How current is the regulatory status information?

Regulatory and licensing data is gathered from public web sources by AI at the time of your request, reflecting the most recently published information. Licensing status can change — we recommend verifying directly with the relevant state authority before making clinical or business decisions.